I found VisualVM (see here and here) to be very convenient. Its use with Clojure has been described about a year ago in this blog post; as far as I can see, it’s not outdated in any way.
Note that the GUI from which one starts the VisualVM profiler has a prominent text area where one can enter classes / packages to be excluded from profiling — I find the results rather more useful when clojure.* is on that list.