os.path.expanduser(path) could be helpful.
On Unix and Windows, return the argument with an initial component of
~userreplaced by that user‘s home directory.
On Unix, an initial
~is replaced by the environment variable HOME if it is set; otherwise the current user’s home directory is looked up in the password directory through the built-in module
pwd. An initial
~useris looked up directly in the password directory.
On Windows, HOME and USERPROFILE will be used if set, otherwise a combination of HOMEPATH and HOMEDRIVE will be used. An initial
~useris handled by stripping the last directory component from the created user path derived above.
If the expansion fails or if the path does not begin with a tilde, the path is returned unchanged.
So you could just do: