You can serve the response as multipart/form-data and use Response.formData() to read response at client
fetch("/path/to/server", {method:"POST", body:formData})
.then(response => response.formData())
.then(fd => {
for (let [key, prop] of fd) {
console.log(key, prop)
}
})
let fd = new FormData();
fd.append("json", JSON.stringify({
file: "image"
}));
fetch("data:image/gif;base64,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")
.then(response => response.blob())
.then(blob => {
fd.append("file", blob);
new Response(fd)
.formData()
.then(formData => {
for (let [key, data] of formData) {
console.log(key, data)
}
})
})